RaDiCo program aims at endowing France with large epidemiological instruments or "cohorts" in the field of rare diseases. These cohorts are designed to improve the understanding of health determinants of rare diseases and ultimately, to the development of new therapeutic strategies. RaDiCo is coordinated by the French Institute on Health and Medical Research (Inserm). It is funded by the French Health Ministry in the framework of the so-called "Investissements d'Avenir" funding scheme. Based in Paris, RaDiCo offers a clinical research and services platform for the translational research on rare diseases.